Peer-Reviewed Clinical Study — March 2026

Build Tissue.
Build Revenue.
Build Smiles.™

The non-surgical, peer-reviewed gum regeneration protocol that 96.5% of patients rated 4 or 5 out of 5 — across 144 patients and 28 dental practices.

144 Patients28 Dental PracticesMarch 2026Peer-Reviewed
78%
Sensitivity Reduction
Clinical Pain Score
32%
Gum Tissue Volume Gain
Large Effect Size
29%
Recession Reduction
Measured Improvement
1085%+
ROI Per Case
Per-Tooth Basis
🔬 FDA 510(k) Cleared Technology🏥 28 Dental Practices Validated📊 Peer-Reviewed Study Data⚡ Same-Day Recovery💰 1,100%+ ROI Per Case
Dental patient receiving gum treatment
57%
of adults have at least one gum recession site

57% of Your Patients Have Gum Recession.
Fewer Than 9% Accept Surgery.

There is a massive, underserved patient population sitting in your chair right now — and the only option you've had to offer them was a procedure they almost universally refuse.

📈

The Prevalence Is Staggering

Over 57% of adults have at least one site with gingival recession. Prevalence increases with age — exactly where patients see and feel it every day.

🚫

Surgery Has a 91% Refusal Rate

Grafting is effective — but invasive, costly, and painful. Fewer than 9% of patients who are recommended grafting actually accept it. The rest walk out untreated.

GumBuilder™ Fills the Gap

A non-surgical, 15-minute chairside protocol for mild–moderate recession. Case acceptance jumps to 50–80% when patients are offered a non-surgical option.

Calcium Hydroxyapatite.
FDA-Cleared. Collagen-Stimulating. Proven.

GumBuilder™ is not a filler. It is a bioactive regenerative protocol that actively stimulates the body's own collagen production — creating lasting structural improvement, not temporary volume.

How CaHA Technology Works

Calcium Hydroxyapatite (CaHA) — the active ingredient in GumBuilder™ — is a naturally occurring mineral found in bone and teeth. When placed subgingivally, CaHA microspheres provide an immediate structural scaffold while simultaneously triggering fibroblasts to produce new collagen.

Unlike traditional fillers that simply add volume, CaHA biostimulates genuine tissue regeneration. The scaffold is gradually resorbed while new collagen fibers replace it — resulting in thicker, healthier, more stable gingival tissue.

79%
Pain Reduction
32%
Volume Gain
29%
Recession Reduction
FDA
510(k)
FDA 510(k) Cleared Since 2003

CaHA cleared to fill/augment dental intraosseous and oral/maxillofacial defects. A single Radiesse injection significantly reduces hypersensitivity vs. fluoride varnish, with effect persisting beyond six months.

The 5-Point Injection Map

1
Mesial Papilla
2
Mesial Midpoint
3
Apex (Mucogingival Junction)
4
Distal Midpoint
5
Distal Papilla
~0.1ml per toothRadiesse (+) CaHA29g Comfortox Syringe
📉Gum Recession
❄️Hypersensitivity
◻️Black Triangles
💎Veneers & Crowns
🔩Dental Implants
🦷Post-Orthodontic
Peer-Reviewed Clinical Data

The Data That Changes Everything.

You now have peer-level clinical data — not just a course claim. That distinction matters enormously to skeptical dentists who have seen plenty of overhyped CE courses.

AAFE Gum Builder StudyProtocol 001March 2026144 Respondents28 Practices0% Missing Data
0%
Sensitivity Reduction
Your headline number — the stat patients feel
0%
Gum Tissue Volume Gain
Large effect size — makes periodontists pay attention
0%
Recession Reduction
The chief complaint that brings patients in
0:1
Improvement-to-Worsening Ratio
Safety stat that answers 'what if it doesn't work?'

Patient Survey Results

144 patients · 6 questions · 1–5 scale

4.58/5
Overall Mean
Overall experience?4.75/5
✓ 96.5% rated 4 or 5 · 78.5% gave a perfect 5
Comfort after appointment?4.72/5
✓ 95.1% rated 4 or 5 · 77% gave a perfect 5
Would you do it again?4.67/5
✓ 91% would repeat treatment
Would you recommend it?4.67/5
✓ 91% would recommend — strong referral signal
Comfort during treatment?4.52/5
✓ 91% rated 4 or 5 during treatment
Noticed sensitivity decrease?4.14/5
✓ 70.1% rated 4 or 5 · 50% complete elimination

Provider Survey Results

28 providers · 144 observations · 5 questions

4.76/5
Overall Mean
Clear to explain to patient?4.88/5
✓ 99.3% rated 4 or 5 · 89% gave a perfect 5
Study admin responsiveness?4.88/5
✓ 97.2% rated 4 or 5 · 91% gave a perfect 5
Overall study experience?4.81/5
✓ 99.3% rated 4 or 5 · 82% gave a perfect 5
Protocol easy to follow?4.86/5
✓ 96.5% rated 4 or 5 · 90% gave a perfect 5
Ease of treatment delivery?4.35/5
✓ 80.6% rated 4 or 5 — hands-on training recommended

Consistent across all 28 practices. No provider had an overall patient mean below 3.83/5, confirming the treatment's acceptability across diverse clinical settings.

"78.5% of patients gave their overall experience a perfect 5 out of 5. Not a single survey question averaged below 4.14."
— AAFE Gum Builder Study — Patient Survey Analysis, March 2026
"99.3% of providers found the treatment clear to explain to patients — across 28 completely different practice settings."
— AAFE Gum Builder Study — Provider Survey Analysis, March 2026
"A top-2 box score above 80% is considered strong in medical device research. Every patient question except sensitivity exceeds 91%."
— AAFE Gum Builder Study — Statistical Summary, March 2026

$12.50 In. $150–$200 Out.
Per Tooth. Every Time.

GumBuilder™ is not just a clinical win — it is one of the highest-margin, lowest-overhead procedures available in modern dentistry. No lab fees. No drilling. No referrals out.

Practice ModelFeeCostNet ProfitROI
GP (per tooth)$150$12.50$137.501,100%
Periodontist (per tooth)$180$12.50$167.501,340%
Perio Premium (per tooth)$200$12.50$187.501,500%
6-Tooth Flat Fee$1,250–$1,500~$153~$1,097–$1,3477–9×
Economy Hygiene$450/case~$153~$297High-Vol
$3,300
Revenue equivalent per hour with GumBuilder™
$300
Revenue equivalent per hour for a composite filling

Your GumBuilder™ Revenue Calculator

Weekly Revenue
$5,000
Weekly Profit
$4,388
Monthly Revenue
$20,000
ROI
717%

Based on ~$153 product cost per case (6-tooth, 2-visit protocol). Individual results vary by practice model and fee structure.

Three Visits. Fifteen Minutes Each.

The GumBuilder™ protocol is engineered for chairside efficiency. No surgery. No sutures. No referrals. Just a simple, repeatable injection protocol that any trained dentist can deliver.

1
Visit 1

Consultation & First Injection

  • Gum Recession & Sensitivity Screen
  • Informed consent & photography
  • Topical anesthetic application (20 min)
  • 5-point CaHA injection map per tooth
  • Post-treatment instructions provided
2
Visit 2

Follow-Up Injection (4–6 Weeks)

  • Clinical assessment of tissue response
  • Photography comparison
  • Second round of CaHA injections
  • Patient satisfaction check-in
3
Visit 3

Final Assessment (3 Months)

  • Final clinical photography
  • Tissue volume and recession measurement
  • Patient survey completion
  • Maintenance protocol established

🗂️ Treatment Tray Setup

💉Radiesse (+) CaHA 1.5ml SyringeCore Product
💉Comfortox 29g SyringeInjection Tool
🧴Topical Anesthetic (20% Benzocaine)Pre-Treatment
🔬Periodontal ProbeAssessment
📸Clinical Camera / Intraoral CameraDocumentation
🔧Coronal PolisherFinishing
🧤Retractors, Gauze & Q-TipsPrep

📦 Order via StatDDS — Official GumBuilder™ Partner

statdds.com/product-category/gum-builder · 1.800.693.9076

Shop GumBuilder Supplies →

⚡ Protocol At a Glance

15
Minutes per visit
2
Visits required
0.1ml
Per tooth volume
5
Injection points per tooth

GumBuilder™ vs. Connective Tissue Graft

GumBuilder™ is not a replacement for grafting — it is the non-surgical alternative for the 91% of patients who decline it. Present grafting as the gold standard, then offer GumBuilder™ as the accessible path forward.

DimensionGumBuilder™Connective Tissue Graft
Procedure TypeNon-surgical injectionSurgical — palatal donor site
AnesthesiaTopical onlyLocal + sedation often required
Chair Time15 minutes per visit60–90 minutes
RecoverySame day, minimal7–14 days, significant discomfort
Patient Acceptance50–80% case acceptance<9% case acceptance
Cost to Patient$150–$200 per tooth$1,500–$4,000+ per site
IndicationMiller Class I–II, mild–moderateAll classes, including severe
Tissue OutcomeBiostimulated collagen regenerationTransplanted donor tissue
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The "Declined Graft" Opportunity

You already have a pipeline of patients who were recommended grafting and said no. Those cases currently generate zero revenue and continue to worsen. GumBuilder™ converts them into high-margin, same-day production — while keeping the patient in your practice instead of referring out.

Five Ways to Integrate GumBuilder™.
From Solo GP to DSO.

GumBuilder™ is engineered with flexible, scalable systems that support every practice model. Choose the framework that fits your practice — or combine multiple approaches.

1

Gum Wellness Integration

Make GumBuilder™ the standard non-surgical treatment for mild–moderate recession within your perio and preventive care programs. Every perio chart includes a Gum Recession & Sensitivity Screen.

Stabilize recession + drive new production
2

Hygiene-Driven Hypersensitivity

Hygienist identifies candidates at every recall appointment. Patients with sensitivity, recession, or black triangles are handed off to the doctor for a 15-minute same-day or scheduled treatment.

Loyalty + recurring GumBuilder™ cases
3

Perio & Grafting Alternative

For perio or GP-perio practices, GumBuilder™ becomes the non-surgical alternative when grafting is refused or delayed. Convert 'declined graft' cases that currently generate zero revenue.

Monetize every declined graft case
4

Esthetic Treatment

Use GumBuilder™ to eliminate black triangles and improve smile esthetics. An ideal add-on for cosmetic-focused practices — patients who care about their smile are already motivated.

High-value esthetic cases
5

DSO / Multi-Location Scale

Standardize the GumBuilder™ protocol across all locations. Centralized training, unified supply chain through StatDDS, and consistent patient experience at scale.

System-wide revenue lift

Watch How GumBuilder™
Changes Dentistry.

From the problem to the protocol to the payoff — see exactly why 500+ practices have already added GumBuilder™.

AI-generated preview — final branded video with motion graphics coming soon.

Get Certified at AAFE →

America's Master Trainers
of Injection Techniques.

GumBuilder™ is an exclusive AAFE protocol. It is only available to AAFE-certified providers — because the training, the technique, and the outcomes are inseparable.

25,000+
Dentists Trained in Facial Esthetics
The largest injection training academy in dentistry
500+
Practices Already GumBuilder™ Trained
And growing every month
200+
More Registered for Upcoming Trainings
Momentum is accelerating
#1
Injection Training Academy for Dentists
Botox · Fillers · GumBuilder™ · More
🎯

Exclusive Protocol Access

GumBuilder™ is not available on the open market. It is an AAFE-exclusive protocol. Only trained and certified AAFE providers can offer it — which means your patients can't get it anywhere else.

AAFE Exclusive
💉

Master Trainers of Injections

AAFE has trained over 25,000 dentists in Botox, dermal fillers, and now GumBuilder™. Our instructors are not just educators — they are active clinicians who perform these procedures daily.

25,000+ Dentists Trained

Train Today. Inject Tomorrow.

No overhead. No additional equipment. No new patient acquisition. Your existing dental patients already have the problems GumBuilder™ solves. You just need the training to treat them.

Same-Week ROI

Train Today. Inject Tomorrow.

1
Register

Choose live or on-demand AAFE GumBuilder™ certification

2
Get Certified

Full protocol, injection technique, scripts, and business system

3
Start Treating

Your existing patients. Your existing practice. Zero new overhead.

Join 500+ Practices Already Trained.
200+ more registered for upcoming trainings. The window to be an early adopter in your market is closing.
Secure Your Spot →
Get Started

Ready to Add GumBuilder™
to Your Practice?

Join the growing network of dentists and periodontists delivering peer-reviewed, non-surgical gum regeneration — and building a new high-margin revenue stream with every hygiene appointment.

🎓
Get AAFE Certified

Live and on-demand courses available. Hands-on training with full clinical protocol, injection technique, and complete business integration system. Train today — inject tomorrow.

View Course at facialesthetics.org →
📋
Full Integration System

Scripts, tray setups, brochures, posters, email templates, ROI calculator, and social media content — everything your team needs to start treating patients immediately after training.

Learn more at AAFE →